Published inDev GeniusR : Graphical Multiple Testing ProcedureBackground Story: In clinical trials, we often encounter situations where there is more than one primary endpoint — such as co-primary…Jun 8Jun 8
Newcombe-Wilson Confidence Intervalbackground story: When comparing response rates between two arms, we typically rely on Fisher’s Exact Test (Clopper-Pearson) to construct…May 28May 28
Randomization Plan with SAS and RBackground Story: Most of the time, the vendor handles the randomization schedule. However, it would be valuable for us to understand the…Mar 10Mar 10
Sample Size Calculation in R and SASBackground Story: One day, I need to validate some sample size results for a study. But my SAS does not work, so I have to use R to…Jan 18Jan 18
Published inDev GeniusSAS Proc Common Statistical ProcedureBackground story: Our SAS system requires an upgrade, and the statistician needs to provide examples of some SAS procedures for a test run…Oct 6, 2024Oct 6, 2024
Published inDev GeniusR PKNCA: PK AUC and T-halftimeBackground Story:In clinical trials, pharmacokinetics (PK) is a crucial aspect of early-stage development. Typically, a PK scientist…May 20, 2024May 20, 2024
Published inDev GeniusPython Multinormal SimulationBackground: One day, we need to simulate data for both the control and treatment groups using a multinormal distribution, which is usually…May 16, 2024May 16, 2024
Published inTowards DevR Cowsay + Praise : celebrate tiny achievement everydayBackground Story: Some people start work by drinking coffee, others do a mediation, today I’d like to share my way of starting and ending…Apr 23, 2024Apr 23, 2024
Published inDev GeniusSAS Multiple Imputation: Proc MI+ MIXED+ MIanalyzeBackground Story: Handling missing data presents a significant challenge in clinical trials. Patients are often lost to follow-up or lack…Apr 15, 2024Apr 15, 2024
Published inDev GeniusMMRM R and SAS code EquivalenceBackground Story: In Clinical trials, SAS predominates the study output, so we might sometimes find it intricate to verify outcomes using…Apr 12, 2024Apr 12, 2024
